Jan 15, 2019
Unchained Labs cuts the ribbon on new contract testing lab in North America! Read more.
Unchained Labs cuts the ribbon on new contract testing lab in North America!
January 15, 2019 – Pleasanton, CA – Unchained Labs, the life sciences company that’s all about getting biologics researchers the right tool for the job, opened the doors to its new contract testing lab today. The lab is located at the company’s headquarters in Pleasanton, California and provides identification of unwanted particles in drug products and quality assessment of the silicone layers on drug delivery devices.
Two Unchained Labs instruments are heavily used for contract testing. For visible particles, Hound determines the count, size, shape and identity with either Raman or LIBS spectroscopy. If clients have particles in the sub-visible range, the lab has the tools to hunt down those too. Bouncer is used to measure the silicone thickness and distribution on syringes, cartridges and vials.
All sample preparation and testing are handled by trained experts who deliver detailed reports that document the test plan, measurement parameters and results. Turnaround time for results can be as quick as 3 days.
“If someone has particle problems or wants to confirm that the right amount of silicone is on their device, we’ve got their back,” said Taegen Clary, VP of Marketing at Unchained Labs. “The new Pleasanton contract testing lab makes it easier for more customers in North America to take advantage of these services and expands capacity beyond our current test lab in Europe.”
About Unchained Labs
Here’s the deal. We’re all about helping biologics researchers break free from tools that just don’t cut it. Unleashing problem-tackling products that make a huge difference in the real science they do every day. That’s our mantra, our promise and we own it. We’re located in Pleasanton, CA and can be found online at www.unchainedlabs.com.
Contact:
Taegen Clary
VP of Marketing, Unchained Labs
taegen.clary@unchainedlabs.com
925.587.9806
Download PDF of press release.
Nov 5, 2018
Unchained Labs takes the chore out of buffer exchange, reels in the Big Tuna! Read more.
Unchained Labs takes the chore out of buffer exchange, reels in the Big Tuna!
November 5, 2018 – Pleasanton, CA – Unchained Labs, the life sciences company that’s all about getting biologics researchers the right tool for the job, launched Big Tuna today – the ultimate automated solution for buffer exchange – a mission-critical step in biologics formulation.
The buffer exchange process moves proteins from one solution into another and is used to find the best condition to keep them stable. It’s a major bottleneck and quality concern for protein characterization, development and formulation teams. Because the process needs lots of hands-on time and eyeballing to do it right, it’s one of the most annoying things researchers have to do.
Big Tuna solves all of this. It wipes the bottleneck by letting scientists automate buffer exchange at whatever throughput they want – just a few samples or up to 96 simultaneously. It nails quality using a unique pressure-based exchange process that lets scientists pick how slow or fast they want their protein to move between solutions. Final protein concentration is dead-on, cutting out extra steps usually required after manual buffer exchange. Big Tuna is also the only system that exchanges anywhere from 100 µL to 8 mL at a time, so it’s right at home in any stage – from early screening and optimization to final formulation development.
“Biologics researchers have bigger fish to fry than buffer exchange,” said Taegen Clary, VP of Marketing at Unchained Labs. “Big Tuna provides complete relief from one of their biggest pains in the neck. It eliminates the whole hands-on process and delivers better results to boot.”
About Unchained Labs
Here’s the deal. We’re all about helping biologics researchers break free from tools that just don’t cut it. Unleashing problem-tackling products that make a huge difference in the real science they do every day. That’s our mantra, our promise and we own it. We’re located in Pleasanton, CA and can be found online at www.unchainedlabs.com.
Contact:
Taegen Clary
VP of Marketing, Unchained Labs
taegen.clary@unchainedlabs.com
925.587.9806
Download PDF of press release.
Oct 8, 2018
Unchained Labs blows minds with biologic quant and quality mashup, launches Stunner! Read more.
Unchained Labs blows minds with biologic quant and quality mashup, launches Stunner!
October 8, 2018 – Pleasanton, CA – Unchained Labs, the life sciences company that’s all about getting biologics researchers the right tool for the job, launched Stunner today — the first instrument to combine protein concentration and size-based quality measurements under the same hood.
Every day, biologics researchers ask themselves two critical questions about their samples: How much protein do I have, and is it in good shape? To get the answers, they typically need to run experiments on multiple instruments, which eats up time and sample. Stunner gives them both in one shot by combining UV/Vis concentration and Dynamic Light Scattering (DLS) quality measurements from the same tiny sample.
Stunner gives scientists the best of two worlds — the dead-on UV/Vis accuracy Unchained Labs’ Lunatic is known for, and the company’s fresh take on DLS technology, which is super easy to use compared to other systems out there. With just 2 µL, Stunner bangs out concentration and quality measurements like hydrodynamic size, polydispersity and detection of aggregates in 1 minute. Researchers dealing with a full plate can knock out 96 samples in an hour. For heavy duty workflows, they can hook Stunner up to their favorite robot to add more zip.
“Biologics researchers have needed a solution like this forever, which makes Stunner a real head-turner,” said Taegen Clary, VP of Marketing at Unchained Labs. “Concentration is something they check constantly and DLS has been notoriously hard to use. Stunner makes it ridiculously easy to get these measurements at the same time on one system and literally makes DLS a push button activity.”
About Unchained Labs
Here’s the deal. We’re all about helping biologics researchers break free from tools that just don’t cut it. Unleashing problem-tackling products that make a huge difference in the real science they do every day. That’s our mantra, our promise and we own it. We’re located in Pleasanton, CA and can be found online at www.unchainedlabs.com.
Contact:
Taegen Clary
VP of Marketing, Unchained Labs
taegen.clary@unchainedlabs.com
925.587.9806
Download PDF of press release.
Aug 20, 2018
Unchained Labs just couldn’t take it anymore, frees the Big Kahuna! Read more.
Unchained Labs just couldn’t take it anymore, frees the Big Kahuna!
August 20, 2018 – Pleasanton, CA – Unchained Labs, the life sciences company that’s all about getting biologics researchers the right tool for the job, renamed its flagship workflow solution today. Freeslate is now the Big Kahuna.
“We really love this product and it deserved to be a part of the Unchained Labs family,” said Taegen Clary, VP of Marketing at Unchained Labs. “It’s always been the Big Kahuna to us and from here on out that’s what we’re going to call it.”
About Unchained Labs
Here’s the deal. We’re all about helping biologics researchers break free from tools that just don’t cut it. Unleashing problem-tackling products that make a huge difference in the real science they do every day. That’s our mantra, our promise and we own it. We’re located in Pleasanton, CA and can be found online at www.unchainedlabs.com.
Contact:
Taegen Clary
VP of Marketing, Unchained Labs
taegen.clary@unchainedlabs.com
925.587.9806
Download PDF of press release.
Apr 30, 2018
Unchained Labs brings in the muscle with Bouncer and releases the Hounds! Read more.
Unchained Labs brings in the muscle with Bouncer and releases the Hounds!
April 30, 2018 – Pleasanton, CA – Unchained Labs, the life sciences company that’s all about getting biologics researchers the right tool for the job, launched Hound and Bouncer today at the PEGS conference in Boston. The QC duo are the ultimate tools for getting biopharmaceutical manufacturers to particle-free biologics and trouble-free drug delivery devices faster.
Particles in a drug formulation throw a wrench into development and manufacturing. Hound uses Raman spectroscopy to fingerprint protein and organic particles. Metal, glass, and other inorganic particles get blasted by Laser-Induced Breakdown Spectroscopy (LIBS) to identify their elemental makeup. In just minutes, researchers can fully ID unwanted particles, find their source and fix their process.
Silicone oil makes a drug injection smooth and easy. Too little and the device can get jammed up. Too much and silicone can ooze into the drug and may cause aggregation. Bouncer lets manufacturers measure the thickness of sprayed-on and baked-on silicone coatings using a combo of reflectometry and interferometry. Scientists can get a handle on their coatings in minutes and fine-tune their process accordingly for top-notch device performance.
“This tag team of QC tools for biologics labs has no equal”, said Taegen Clary, VP of Marketing at Unchained Labs. “Hound goes way beyond just finding particles – it forensically identifies them by what they’re made of. Bouncer helps dial in the silicone coating process, ensuring delivery devices work every time and are as safe as possible.”
About Unchained Labs
Here’s the deal. We’re all about helping biologics researchers break free from tools that just don’t cut it. Unleashing problem-tackling products that make a huge difference in the real science they do every day. That’s our mantra, our promise and we own it. We’re located in Pleasanton, CA and can be found online at www.unchainedlabs.com.
Contact:
Taegen Clary
VP of Marketing, Unchained Labs
taegen.clary@unchainedlabs.com
925.587.9806
Download PDF of press release.
Apr 16, 2018
Unchained Labs crushes it with Uncle 3.0! Read more.
Unchained Labs crushes it with Uncle 3.0!
April 16, 2018 – Pleasanton, CA – Unchained Labs, the life sciences company that’s all about getting biologics researchers the right tool for the job, released its Uncle 3.0 software today. This update adds a brand-spanking new application and makes Uncle QC-ready for biologics labs.
When formulating proteins at high concentrations, G22 measurements are the only way for scientists to quickly tell if a formulation makes their protein more apt to stick to itself or not. Uncle is the first platform to give researchers a G22 for their biologic with just a click of a button, letting them check for attractive forces that could cause aggregation troubles later on.
For scientists working in regulated environments, where controlling access to data and keeping its integrity are a must-have, the new 21 CFR Part 11-compliant software tools in Uncle 3.0 software can be turned on without a hitch.
“Uncle’s still the go-to instrument for screening protein stability. With the 3.0 release, high-concentration biologics can be assessed earlier in development. That’s a huge deal because these formulations are more effective and can be dosed less often, but are also at higher risk for aggregation,” said Taegen Clary, VP of Marketing at Unchained Labs. “The new compliance features we’ve added to our Uncle also make it a piece of cake for customers to transfer their applications to QC.”
About Unchained Labs
Here’s the deal. We’re all about helping biologics researchers break free from tools that just don’t cut it. Unleashing problem-tackling products that make a huge difference in the real science they do every day. That’s our mantra, our promise and we own it. We’re located in Pleasanton, CA and can be found online at www.unchainedlabs.com.
Contact:
Taegen Clary
VP of Marketing, Unchained Labs
taegen.clary@unchainedlabs.com
925.587.9806
Download PDF of press release.
Mar 27, 2018
Unchained Labs keeps them coming, acquires rap.ID! Read more.
Unchained Labs keeps them coming, acquires rap.ID!
March 27, 2018 – Pleasanton, CA – Unchained Labs, the life sciences company that’s all about getting biologics researchers the right tool for the job, acquired rap.ID today. Rap.ID is a leading provider of systems used for particle identification in biopharmaceutical development and quality control. The company also provides contract services in these areas. This is Unchained Labs’ 6th acquisition in just over 3 years.
Particles muck up the quality of a drug and can shut down its production. Single Particle Explorer is the only tool out there that identifies particles by their shape and then forensically identifies them by their chemical and elemental fingerprints. In minutes, researchers know the culprit without a doubt, can track it back to the source, and fix their workflow or manufacturing process.
Silicone oil makes it easier to dispense drugs from injectable devices. Layer Explorer lets researchers measure the thickness and consistency of the silicone, so they can fine-tune their processes to use only a thin, uniform layer to minimize the amount that gets into their formulation.
“These products are great additions to our biologics tools arsenal. We can now help our customers identify the source of any particle that shows up in their process,” said Tim Harkness, Founder and CEO of Unchained Labs. “This acquisition expands our portfolio firmly downstream into biologic quality control.”
“Unchained Labs is an ideal home for our products and employees,” said Dr. Oliver Valet, Managing Director of rap.ID. “They have a great platform to help realize the potential for our products.”
In just over 3 years, Unchained Labs has grown to over 180 employees, $50M+ in revenue, 9 product lines and has direct distribution around the world. In connection with this transaction, the company raised $17M in a Series D financing. Novo Ventures, Canaan Partners, TPG Biotech and Tri-Valley Ventures all participated in the financing.
About Unchained Labs
Here’s the deal. We’re all about helping biologics researchers break free from tools that just don’t cut it. Unleashing problem-tackling products that make a huge difference in the real science they do every day. That’s our mantra, our promise and we own it. We’re located in Pleasanton, CA and can be found online at www.unchainedlabs.com.
Contact:
Taegen Clary
VP of Marketing, Unchained Labs
taegen.clary@unchainedlabs.com
925.587.9806
Download PDF of press release.
Jan 8, 2018
Unchained Labs gives Lunatic a boost, nails high-end biologic quant! Read more.
Unchained Labs gives Lunatic a boost, nails high-end biologic quant!
January 8, 2018 – Pleasanton, CA – Unchained Labs, the life sciences company that’s all about getting biologics researchers the right tool for the job, amped up the protein quant range on Lunatic today, making measurements of up to 250 mg/mL IgG a cinch for biologics researchers.
High-concentration biologics don’t have to be administered as often, plus patients see better results. Lunatic’s new IgG Quant app hits the upper analysis range needed to measure these protein drugs, and does it with only 2 µL of sample straight up – no dilution needed.
Lunatic is the go-to, high-throughput tool for measuring biologic concentrations – from early research to QC. Other tools are kluge, run only a handful of samples at a time, require sample dilution which can skew results, or use way too much sample for early-stage analysis.
“What makes Lunatic special is that it can now reach the protein quant range scientists are really looking for,” said Taegen Clary, VP of Marketing at Unchained Labs. “Because Lunatic uses super small volumes, it can be used upstream when there’s boatloads of samples but not much of them to work with and downstream when there’s buckets of only a few that need analysis. So it’s the ideal tool for measuring protein concentration at all stages of biologics development.”
About Unchained Labs
Here’s the deal. We’re all about helping biologics researchers break free from tools that just don’t cut it. Unleashing problem-tackling products that make a huge difference in the real science they do every day. That’s our mantra, our promise and we own it. We’re located in Pleasanton, CA and can be found online at www.unchainedlabs.com.
Contact:
Taegen Clary
VP of Marketing, Unchained Labs
taegen.clary@unchainedlabs.com
925.587.9806
Download PDF of press release.
