UV/Vis spectroscopy is one of the oldest and most well-established techniques to quantify DNA or RNA and determine nucleic acid quality. Unchained Labs pushes UV/Vis to the next level with innovative optics, optimized consumables and robust analytical techniques.
Big Lunatic and Stunner deliver highly accurate nucleic acid quantification with A260 values from 0.03–275 OD quickly and without dilution. That means you can measure dsDNA concentrations between 1.5–13,750 ng/µL for up to 96 samples in 10 minutes. With Unmix applications or A260/A280 and A260/A230 ratios you can determine sample quality and unravel even the dirtiest samples. If you need more information on UV/Vis spectroscopy for nucleic acids, check out this tech note all about DNA quantification and quality.
Unchained Labs UV/Vis instruments deliver:
Big Lunatic makes batch quantification of RNA or DNA a no-brainer. All you need is 2 µL and 10 minutes to measure up to 96 samples. Run them straight-up, even at high concentrations, without ever diluting. Measurements are spot-on with precision within 1% and accuracy within 2% and are fully compliant with USP and Ph. Eur. guidelines. The SBS plate-based format means integrating with lab automation and liquid handlers is a snap. Big Lunatic gets biologics UV/Vis quantification on the money every time. Just drop, load, and read.
Want to check if your sample is now a blob of aggregates? Stunner combines Big Lunatic’s plate-based, high-throughput UV/Vis accuracy and precision with dynamic light scattering for a one-of-a-kind combination. Pairing up these techniques checks concentration, hydrodynamic size, polydispersity, and detection of aggregates off your to-do list in one shot. Prove that you can trust the data and the sample you hand off to the next scientist.
Little Lunatic is there for labs that have fewer samples and lower requirements. It uses a chip-based version of the Big Lunatic plate to get quick concentration measurements of up to 16 samples in 5 minutes. Researchers that just need a quick check of concentration can get what they need from this little guy and its glove-friendly touch screen.
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