Buffer exchange & sample preparation
Buffer exchange and sample concentration is part of everyday life for scientists working with antibodies and recombinant proteins. Whether it’s for sample prep, preparing for labeling or characterization, or developing formulation screening and optimization strategies for a biologic, the process is monotonous, labor-intensive, time-consuming, and prone to error.
Conventional buffer exchange methods like dialysis and centrifugal filtration suffer from inconsistency in results and are often hard to manage in larger numbers. Sample concentration is usually an additional time-consuming step. Most methods require hands-on time, taking researchers away from other critical work.
The right tool for the job
Fast formulation screening and optimization
Screening for the optimal pH for your antibody is easier than ever before. It only takes 30 minutes to set up and you’ll be running your stability measurements in no time.
Dialing in your formulation
Buffer exchange and sample concentration are the time consuming, hands-on chores you have to deal with before all the things you really want to do. Big Tuna automates exchange to formulate, concentrate and clean up proteins or gene therapy vectors like AAVs, LNPs, and VLPs — with just 30 mins of setup time. Skip the slow and manual ways of prepping samples to free yourself up for other critical work.
Want more info?
Want to learn more about how Big Tuna frees you up from buffer exchange?