AAV concentration & reformulation
AAVs are often produced in dilute volumes that need to be cleaned up and concentrated. Tackling this process with centrifugal filtration devices or one at a time flow filtration instruments is labor intensive, especially at high sample numbers and volumes. Viral vectors like AAV need rapid clean up and buffer exchange workflows that don’t compromise the integrity of the sample and have high recovery.
The right tools for the job
Get your AAV to its happy place
Buffer exchange and concentration are two of the most annoying things you have to do before you can work with your sample. It takes forever, you physically have to be there and just when you think it’s done, you’re tweaking it again. Unagi is the first completely hands-free benchtop buffer exchange solution that’s made to take this not-so-fun task off your plate — so you can be anywhere else instead of tied to your bench.
Buffer exchange and sample concentration are the time consuming, hands-on chores you must deal with before all the things you really want to do. Big Tuna is a fully automated, plate-based buffer exchange platform that uses a modified UF/DF method and gentle mixing to buffer exchange, concentrate, and clean up proteins, nucleic acids, or gene therapy vectors like AAVs and LNPs. Skip the slow and manual ways of prepping samples to free yourself up for other critical work.
Want more info?
Want to learn more about how Unagi and Big Tuna can handle your AAV concentration and reformulation with ease?