AAV reformulation & concentration
AAVs are often produced in dilute volumes that need to be cleaned up and concentrated. Tackling this process with centrifugal filtration devices or one at a time flow filtration instruments is labor intensive, especially at high sample numbers and volumes. Viral vectors like AAV need rapid clean up and buffer exchange workflows that don’t compromise the integrity of the sample and have high recovery.
The right tool for the job
Crank up the concentration
AAVs need to be concentrated up to do formulation work, for storage, or for characterization. Big Tuna can concentrate these up to 100x - from 48 mL to 450 µL. The 24-well, 30 kDa Unfilter keeps the AAV above the membrane while rapidly removing unwanted volume and handling the AAV with care.
Get your AAV to its happy place
Buffer exchange and sample concentration are the time consuming, hands-on chores you have to deal with before all the things you really want to do. Big Tuna automates exchange to formulate, concentrate and clean up proteins or gene therapy vectors like AAVs, LNPs, and VLPs — with just 30 mins of setup time. Skip the slow and manual ways of prepping samples to free yourself up for other critical work.
Want more info?
Want to learn more about how Big Tuna handles your AAV and gene therapy molecules with ease?