Stability & formulation screening
Misbehaving proteins can unfold, aggregate and ruin everything, but the right protein construct will hold it together and save the day. Once you’ve got the right protein, picking formulations is the next big hurdle. Screening for the best proteins and formulations requires having all the right data to advance the best candidates.
Outdated ways of looking at protein stability take way too much sample and time, and often deliver only part of the story. To keep an eye on all the ways that protein stability can go wrong, unfolding and aggregation have to be measured at the same time on the same sample. Plus, the earlier you can weed out bad candidates, the better – so it’s critical to use tiny amounts of protein.
The right tool for the job
How Uncle spots stability problems
Mix it up
Stack the deck
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