Nanoparticle concentration & sizing
The problem
Gathering the basics when characterizing nanoparticles, like figuring out how many you’ve got and what size they are, can be the bottleneck in the nanoparticle manufacturing workflow. Nanoparticle size and concentration are a critical parameters that researchers want to know about every batch of particles, but current methods can’t keep up with throughput, require dilutions that impact accuracy, or are just plain slow.
Building up a stash of nanoparticle sizing data is everyone's goal since keeping particles the right size is the key to their success. But gathering size data on every sample can be a challenge when your only option is to measure samples one at a time.
The right tool for the job
Stunner's rotating angle dynamic light scattering (RADLS) combines size data from multiple angles to see all nanoparticle sizes present, even small populations of aggregates lurking in the background. Pair up RADLS with intelligent, short pathlength UV/Vis to simultaneously quantify total RNA, even in cloudy nanoparticle samples. All done with just 2 µL in under 2 minutes per sample for up to 96 samples at a time.
The proof
Take it for a spin
LNPs are huge and have crazy scatter effects, but they're no match for Stunner's one-of-a-kind rotating angle DLS. RADLS provides angle-independent sizing and light scattering intensity of your nanoparticle sample. Getting nanoparticle concentration has never been easier.
Get it together
Stunner
Stunner is the only nanoparticle concentration and sizing system that pulls together UV/Vis concentration, rotating angle dynamic light scattering (RADLS) and multi-angle static light scattering (MALS) data from the same 2 μL sample. Nail down your lipid nanoparticle quality by knocking out particle concentration, size, polydispersity, aggregate detection and total RNA off your list in one shot. Without skipping a beat, you'll know if your nanoparticle is good to go.
FAQs
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